Oligoclonal IgM bands are a promising biomarker for long-term cognitive outcomes in multiple sclerosis

C Coll-Martinez, E Quintana, M Buxó… - Multiple Sclerosis and …, 2022 - Elsevier
… The presence of oligoclonal IgM bands (OCMB) in CSF and, more specifically, lipid-specific
from clinically isolated syndrome to relapsing-remitting multiple sclerosis (MS) as well as …

Oligoclonal IgM bands in the cerebrospinal fluid of patients with relapsing MS to inform long-term MS disability

…, S Alba-Arbalat, M Sepulveda… - Multiple Sclerosis …, 2021 - journals.sagepub.com
… Demographic features, IgM index, oligoclonal IgM bands (OCMB), lipid-specific OCMB,
CSF … and CSF NfL levels when measured at the early RMS stage to predict long-term retinal …

[HTML][HTML] Increased intrathecal neurofilament light and immunoglobulin M predict severe disability in relapsing-remitting multiple sclerosis

I Rosenstein, S Rasch, M Axelsson… - Frontiers in …, 2022 - frontiersin.org
Predicting aggressive multiple sclerosis with intrathecal igm synthesis among patients
with a clinically isolated syndrome. Neurology(R) Neuroimmunol Neuroinflamm (2021) 8(5):e1047…

[HTML][HTML] Cerebrospinal fluid igm and oligoclonal igg bands in multiple sclerosis: A meta-analysis of prevalence and prognosis

M Fonderico, E Portaccio, L Razzolini, L Pastò… - Brain Sciences, 2021 - mdpi.com
… Accumulating evidence shows the positive long-term impact … in the CSF is 200 times less
than IgG, immunoglobulins M are … antigens and named those bands lipid-specific OCMBs (LS-…

Is it cost-effective to request IgM oligoclonal bands against lipids in daily practice as a biomarker for poor prognosis in multiple sclerosis?

SR García, J Castillo-Villalba, RG Rubio… - Multiple Sclerosis and …, 2023 - Elsevier
… against lipids negatively impact multiple sclerosis prognosis. … their cerebrospinal fluid (CSF),
while those with negative IgG … the Multiple Sclerosis Functional Composite (MSFC) and the …

[PDF][PDF] CSF biomarkers in multiple sclerosis: Beyond neuroinflammation

S Toscano, F Patti - Neuroimmunol. Neuroinflamm, 2021 - pdfs.semanticscholar.org
Lipid-specific IgM OCB are associated with higher risk of … Lipid-specific IgM OCB predict a
decreased response to IFN-… In CIS patients with optic neuritis, CSF NF-L predicted long-term

[HTML][HTML] Assessing the presence of oligoclonal IgM bands as a prognostic biomarker of cognitive decline in the early stages of multiple sclerosis

…, M Buxó, M González‐del‐Rio… - Brain and …, 2021 - ncbi.nlm.nih.gov
lipidspecific oligoclonal IgM bands as a prognostic biomarker of cognitive impairment in the
early stages of multiple sclerosis… for predicting cognitive outcomes at middle or long term is …

[HTML][HTML] A scoping review on body fluid biomarkers for prognosis and disease activity in patients with multiple sclerosis

N Barizzone, M Leone, A Pizzino, I Kockum… - Journal of Personalized …, 2022 - mdpi.com
… These confirm the role of oligoclonal bands, immunoglobulin free light chain and chitinase
CHI3L1 in CSF and of serum vitamin D in the prediction of conversion from CIS to clinically …

[HTML][HTML] High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis

I Rosenstein, M Axelsson, L Novakova… - Frontiers in …, 2023 - frontiersin.org
… synthesis (ITMS) determined with lipid-specific oligoclonal IgM bands (LS-OCMB) on IPS
worsening in RRMS (43). In fact, except for the long-term storage, assessed with the selective …

[图书][B] Biomarkers in Multiple Sclerosis

V Ignatova - 2022 - intechopen.com
… In CIS patients without ON, CSF NF-L predicts long-term … In patients with CIS, the identification
of CSF lipid-specific IgM OCB is … of CSF IgM OCB in patients with CIS predicted another …